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  • Kumar, V. A. et al. Highly angiogenic peptide nanofibers. ACS nano 9, 860-868, doi:10.1021/nn506544b (2015).
  • Dong, H., Paramonov, S. E., Aulisa, L., Bakota, E. L. & Hartgerink, J. D. Self-assembly of multidomain peptides: balancing molecular frustration controls conformation and nanostructure. J. Am. Chem. Soc. 129, 12468-12472, doi:10.1021/ja072536r (2007).
  • Aulisa, L., Dong, H. & Hartgerink, J. D. Self-assembly of multidomain peptides: sequence variation allows control over cross-linking and viscoelasticity. Biomacromolecules 10, 2694-2698, doi:10.1021/bm900634x (2009).
  • Galler, K. M., Aulisa, L., Regan, K. R., D’Souza, R. N. & Hartgerink, J. D. Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading. J. Am. Chem. Soc. 132, 3217-3223, doi:10.1021/ja910481t (2010).
  • Wang, Y. et al. Peptide nanofibers preconditioned with stem cell secretome are renoprotective. Journal of the American Society of Nephrology : JASN 22, 704-717, doi:10.1681/ASN.2010040403 (2011).
  • Bakota, E. L., Sensoy, O., Ozgur, B., Sayar, M. & Hartgerink, J. D. Self-assembling multidomain peptide fibers with aromatic cores. Biomacromolecules 14, 1370-1378, doi:10.1021/bm4000019 (2013).
  • Kumar, V. A. et al. Drug-triggered and cross-linked self-assembling nanofibrous hydrogels. J. Am. Chem. Soc. 137, 4823-4830, doi:10.1021/jacs.5b01549 (2015).
  • Kumar, V. A. et al. Self-assembling multidomain peptides tailor biological responses through biphasic release. Biomaterials 52, 71-78, doi:10.1016/j.biomaterials.2015.01.079 (2015).
  • Kumar, V. A. et al. Treatment of hind limb ischemia using angiogenic peptide nanofibers. Biomaterials 98, 113-119, doi:10.1016/j.biomaterials.2016.04.032 (2016).
  • D’Andrea, L. D. et al. Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide. Proceedings of the National Academy of Sciences of the United States of America 102, 14215-14220, doi:10.1073/pnas.0505047102 (2005).
  • Fowkes, F. G. R. et al. Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis. The Lancet 382, 1329-1340 (2013).
  • Hirsch, A. T. & Duval, S. The global pandemic of peripheral artery disease. The Lancet 382, 1312-1314 (2013).
  • Webber, M. J. et al. Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair. Proc Natl Acad Sci U S A 108, 13438-13443, doi:10.1073/pnas.1016546108 (2011).
  • Phelps, E. A. & Garcia, A. J. Engineering more than a cell: vascularization strategies in tissue engineering. Curr. Opin. Biotechnol. 21, 704-709, doi:10.1016/j.copbio.2010.06.005 (2010).
  • Phelps, E. A., Landazuri, N., Thule, P. M., Taylor, W. R. & Garcia, A. J. Bioartificial matrices for therapeutic vascularization. Proc Natl Acad Sci U S A 107, 3323-3328, doi:10.1073/pnas.0905447107 (2010).
  • D’Andrea, L. D. et al. Targeting angiogenesis: structural characterization and biological properties of a de novo engineered VEGF mimicking peptide. Proceedings of the National Academy of Sciences of the United States of America 102, 14215-14220, doi:10.1073/pnas.0505047102 (2005).
  • Santulli, G. et al. In vivo properties of the proangiogenic peptide QK. Journal of translational medicine 7, 41, doi:10.1186/1479-5876-7-41 (2009).
  • Finetti, F. et al. Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis. Biochem Pharmacol 84, 303-311, doi:10.1016/j.bcp.2012.04.011 (2012).
  • Koepsel, J. T., Nguyen, E. H. & Murphy, W. L. Differential effects of a soluble or immobilized VEGFR-binding peptide. Integrative biology : quantitative biosciences from nano to macro 4, 914-924, doi:10.1039/c2ib20055d (2012).
  • Liu, X. et al. Osmotic drug delivery to ischemic hindlimbs and perfusion of vasculature with microfil for micro-computed tomography imaging. J Vis Exp, doi:10.3791/50364 (2013).
  • Leslie-Barbick, J. E., Saik, J. E., Gould, D. J., Dickinson, M. E. & West, J. L. The promotion of microvasculature formation in poly(ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide. Biomaterials 32, 5782-5789, doi:10.1016/j.biomaterials.2011.04.060 (2011).
  • Moon, J. J. et al. Biomimetic hydrogels with pro-angiogenic properties. Biomaterials 31, 3840-3847, doi:10.1016/j.biomaterials.2010.01.104 (2010).
  • Liu, X. et al. In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane. Nanoscale 4, 2720-2727, doi:10.1039/c2nr00001f (2012).
  • Liu, Q. et al. Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells. J. Cell. Physiol. 227, 2907-2916, doi:10.1002/jcp.23035 (2012).
  • Liu, X. et al. Targeted delivery of carbaprostacyclin to ischemic hindlimbs enhances adaptive remodeling of the microvascular network. Hypertension 61, 1036-1043, doi:10.1161/HYPERTENSIONAHA.111.00458 (2013).
  • Terry, T. et al. CD34(+)/M-cadherin(+) bone marrow progenitor cells promote arteriogenesis in ischemic hindlimbs of ApoE(-)/(-) mice. PloS one 6, e20673, doi:10.1371/journal.pone.0020673 (2011).
  • Kedward, J. & Dakin, L. A qualitative study of barriers to the use of statins and the implementation of coronary heart disease prevention in primary care. The British journal of general practice : the journal of the Royal College of General Practitioners 53, 684-689 (2003).
  • Rzouq, F. S. et al. Hepatotoxicity fears contribute to underutilization of statin medications by primary care physicians. The American journal of the medical sciences 340, 89-93, doi:10.1097/MAJ.0b013e3181e15da8 (2010).
  • Yarzebski, J. et al. A community-wide survey of physician practices and attitudes toward cholesterol management in patients with recent acute myocardial infarction. Archives of internal medicine 162, 797-804 (2002).
  • Nguyen, T. A., Diodati, J. G. & Pharand, C. Resistance to clopidogrel: a review of the evidence. Journal of the American College of Cardiology 45, 1157-1164 (2005).
  • Wiviott, S. D. & Antman, E. M. Clopidogrel resistance: a new chapter in a fast-moving story. Circulation 109, 3064-3067, doi:10.1161/01.cir.0000134701.40946.30 (2004).
  • Hiatt, W. R., Money, S. R. & Brass, E. P. Long-term safety of cilostazol in patients with peripheral artery disease: the CASTLE study (Cilostazol: A Study in Long-term Effects). Journal of vascular surgery 47, 330-336, doi:10.1016/j.jvs.2007.10.009 (2008).
  • Hirsch, A. T., Hartman, L., Town, R. J. & Virnig, B. A. National health care costs of peripheral arterial disease in the Medicare population. Vascular medicine 13, 209-215, doi:10.1177/1358863X08089277 (2008).
  • Mahoney, E. M. et al. Vascular hospitalization rates and costs in patients with peripheral artery disease in the United States. Circulation. Cardiovascular quality and outcomes 3, 642-651, doi:10.1161/CIRCOUTCOMES.109.930735 (2010).
  • Elbert, D. L. Liquid-liquid two phase systems for the production of porous hydrogels and hydrogel microspheres for biomedical applications: A tutorial review. Acta biomaterialia 7, 31-56, doi:10.1016/j.actbio.2010.07.028 (2011).
  • Jones, W. S. et al. Trends in settings for peripheral vascular intervention and the effect of changes in the outpatient prospective payment system. Journal of the American College of Cardiology 65, 920-927, doi:10.1016/j.jacc.2014.12.048 (2015).
  • Vinit N. Varu, M. E. H., Melina R. Kibbe. Critical Limb Ischemia. Journal of vascular surgery 51, 230-241 (2010).
  • S. Shi, P. Nguyen, H. Cabral, R. Diez-Barroso, P. Derry, S. Kanahara, V. Kumar*. Development of peptide inhibitors of HIV transmission. Bioactive Materials, 1, 109, 2016
  • V. Kumar, Q. Liu, N. Wickremasinghe, Siyu Shi, T. Cornwright, Y. Deng, A. Azares, A. Jake, N. Agudo, S. Pan, D. Woodside, J. Willerson, R. Dixon and J. Hartgerink. Treatment of hind limb ischemia using angiogenic peptide nanofibers. Biomaterials, 98, 113, 2016
  • V. Kumar*, B. Wang, and S. Kanahara. Rational design of fiber forming supramolecular structures. Experimental Biology and Medicine, 241, 899, 2016
  • V. Kumar, N. Wickremasinghe, S. Shi, J. Hartgerink. A nanofibrous snake venom based hemostat. ACS Biomaterials Science and Engineering, 1, 12, 1300, 2015
  • V. Kumar, B. Wang, S. Shi, I. Li, A. Jalan, B. Sarkar, N. Wickremasinghe and J. Hartgerink. Drug-triggered and crosslinked self-assembling nanofibrous hydrogels. Journal of the American Chemical Society, 137, 14, 4823, 2015
  • V. Kumar, N. Taylor, S. Shi, N. Wickremasinghe, R. D’Souza and J. Hartgerink. Self-assembling multidomain peptides modulate immune responses through biphasic release. Biomaterials, 52, 71, 2015
  • V. Kumar, N. Taylor, S. Shi, B. Wang, A. Jalan, M. Kang, N. Wickremasinghe and J. Hartgerink. Highly Angiogenic Peptide Nanofibers. ACS Nano, 9, 860, 2015
  • V. Kumar, R. Vissapragada, L. Hwang, M. Fusco, C. Ogilvy, A. Thomas. Cerebral AVMs and dural AVFs: Pathology and management. Endovascular Today, 14, 2, 2015
  • N. Wickremasinghe, V. Kumar, Siyu Shi and J. Hartgerink. Controlled angiogenesis in peptide nanofiber composite hydrogels. ACS Biomaterials Science and Engineering, 1, 845, 2015
  • R. Vissapragada, V. Kumar, O. Merchant, L. Hwang, M. Fusco, C. Ogilvy, A. Thomas. Material Requirements for Therapeutic Embolization of Intracranial Vascular Malformations. Endovascular Today, 14, 4, 2015.
  • L. Hwang, V. Kumar, R. Vissapragada, K. Lui, M. Fusco, C. Ogilvy, A. Thomas. Treatment Options for Cerebral AVMs and Dural AVFs Endovascular Today, 14, 3, 2015.
  • V. Kumar, N. Taylor, A. Jalan, L. Hwang, B. Wang and J. Hartgerink. A nanostructured collagen mimic for hemostasis. Biomacromolecules, 15, 4, 1484, 2014
  • V. Kumar, A. Martinez, J. Caves, N. Naik, C. Haller and E. Chaikof. Microablation of collagen-based substrates for tissue engineering. Biomedical Materials, 9,1, 1002, 2014
  • N. Wickremasinghe, V. Kumar, J. Hartgerink. Two step self-assembly of liposome-multidomain peptide nanofiber hydrogel for time-controlled release. Biomacromolecules, 15, 10, 3587, 2014
  • R. Vissapragada, M. Contreras, C. DaSilva, V. Kumar, A. Ochoa, A. Vasudevan, C. Ferran and A. Thomas. Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit. Cover art. Brain Research, 1561, 8, 2014
  • V. Kumar, J. Caves, C. Haller, E. Dai, L. Liu, S. Grainger and E. Chaikof. Mechanically tunable extracellular matrix mimetics for soft tissue engineering. Biomaterials Science, 1, 11, 1193, 2013
  • V. Kumar, J. Caves, C. Haller, E. Dai, L. Liu, S. Grainger and E. Chaikof. Acellular Vascular Grafts Generated from Collagen and Elastin Analogues. Acta Biomaterialia, 9, 3, 8067, 2013
  • Z. Qu, S. Muthukrishnan, M. Urlam, C. Haller, S. Jordan, V. Kumar, U. Marzec, Y. Elkasabi, J. Lahann, S. Hanson, E. Chaikof. A biologically active surface enzyme assembly that attenuated thrombus formation. Advanced Functional Materials, 21, 24, 4746, 2011
  • N. Naik, V. Kumar, E. Chaikof and M. Allen. MEMS-assisted spatially homogeneous endothelialization of a high length-to-depth aspect ratio microvascular network. IEEE Eng Med Bio Soc., 8, 290, 2011
  • V. Kumar, L. Brewster, J. Caves, E. Chaikof. Tissue Engineering of blood vessels: current status, requirements and future challenges. Cardiovascular Engineering and Technology, 2, 3, 137, 2011
  • J. Caves, W. Cui, J. Wen, V. Kumar, A. Martinez, E. Chaikof. Elastin-like protein matrix reinforced with collagen microfibers for soft tissue repair. Biomaterials, 32, 23, 5371, 2011
  • J. Wilson, W. Cui, V. Kozlovskaya, E. Kharlampieva, D. Pan, Z. Qu, V. Krishnamurthy, J. Mets, V. Kumar, J. Wen, Y. Song, V. Tsukruk, and E. Chaikof. Cell Surface Engineering with Polyelectrolyte Multilayer Thin Films. Journal of the American Chemical Society, 133, 18, 7054, 2011
  • J. Caves%, V. Kumar%, A. Martinez, J. Kim, C. Ripberger, C. Haller, E. Chaikof. The use of microfiber composites of elastin-like protein matrix reinforced with synthetic collagen in the design of vascular grafts. (% co-first authorship) Biomaterials, 31, 7175, 2010.
  • J. Caves, V. Kumar, W. Xu, N. Naik, M. Allen, E. Chaikof. Microcrimped collagen fiber-elastin composites. Advanced Materials 24, 2041, 2010. Research Highlights, Nature Materials 9, 285, 2010
  • J. Caves, V. Kumar, J. Wen, W. Cui, A. Martinez, R. Apkarian, J. Coats, K. Berland, E. Chaikof. Fibrillogenesis in continuously spun synthetic collagen fiber. Journal of Biomedical Materials Research Part B. Applied Biomaterials, 93b, 24, 2009
  • N. Naik, J. Caves, V. Kumar, E. Chaikof, M. Allen. A template-based fabrication technique for spatially-designed polymer micro/nanofiber composites. Transducers, 21, 1869, 2009
  • A. Webb, V. Kumar and G. Ameer. Biodegradable poly(diol citrate) nanocomposite elastomers for soft tissue engineering. Journal of Materials Chemistry, 17, 900, 2007

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